Publications

See also my Researchgate profile

2017

Fluorogenic labeling strategies for biological imaging.
International Journal of Molecular Sciences 18, 1473 (2017).
C. Li, A. G. Tebo & A. Gautier

Hybrid fluorescent probes for imaging cellular proteins on demand.
Médecine/Sciences 33 (6-7), 576-578 (2017).
L. Jullien & A. Gautier

Membrane-impermeant fluorogenic chromophores.
Patent Application number : EP17305591.4
A. Gautier, L. Jullien, C. Li, F. Perez

Dynamic multi-color protein labeling in living cells.
Chemical Science 8, 5598–5605 (2017) 
C. Li, M.-A. Plamont, H. Sladitschek, V. Rodrigues, I. Aujard, P. Neveu, T. Le Saux, L. Jullien & A. Gautier

PSL Chemical Biology Symposium First 2016 Edition: When Chemistry and Biology share the language of discovery.
ChemBioChem 18, 883-887 (2017).
A. Gautier & R. Rodriguez

2016

Design and characterization of red fluorogenic push-pull chromophores holding great potential for biosensing and imaging.
Organic and Biomolecular Chemistry 14, 9253-9261 (2016).
Li, C., Plamont, M.-A., Aujard, I., Le Saux, T., Jullien, L. & Gautier, A.

Kinetics of reactive modules adds discriminative dimensions for selective cell imaging.
ChemPhysChem 17, 1396-1413 (2016).
Quérard, J., Le Saux, T., Gautier, A., Alcor, D., Croquette, V., Gosse, C., Lemarchand, A. & Jullien, L.

A small fluorescence-activating and absorption-shifting tag for tunable protein imaging in vivo.
Proceedings of the National Academy of Sciences (PNAS) 113 (3), 497-502 (2016).   
Plamont, M.-A., Billon-Denis, E., Maurin, S., Gauron, C., Pimenta, F. M., Specht, C. G., Shi, J., Querard, J., Pan, B., Rossignol, J., Moncoq, K., Morellet, N., Volovitch, M., Lescop, E., Chen, Y., Triller, A., Vriz, S., Le Saux, T., Jullien, L. & Gautier, A.
Highlighted in ‘This week in PNAS’ in PNAS 113 (3), 465-467 (2016).

2015

Fluorogen-based reporters for fluorescence imaging: a review.
Methods and Applications in Fluorescence 3, 042007 (2015).
Jullien, L. & Gautier, A.

Light-activated proteolysis for the spatiotemporal control of proteins.
ACS Chemical Biology 10, 1643-1647 (2015). 
Delacour, Q., Li, C., Plamont, M.-A., Billon-Denis, E., Aujard, I., Le Saux, T., Jullien, L. & Gautier, A.

Expanding discriminative dimensions for analysis and imaging.
Chemical Science 6, 2968-2978 (2015). 
Querard, J., Gautier, A.*, Le Saux, T.* & Jullien, L.*

Photoswitching kinetics and phase sensitive detection add discriminative dimensions for selective fluorescence imaging.
Angewandte Chemie International Edition 54, 2633-2637 (2015).
Querard, J., Markus, T.-Z., Plamont, M.-A., Gauron, C., Wang, P., Espagne, A., Volovitch, M., Vriz, S., Croquette, V., Gautier, A.*, Le Saux, T.* & Jullien, L.*

Preface. Site-specific protein labeling
Site-Specific Protein Labeling: Methods and Protocols, Methods in Molecular Biology, Vol. 1266 (Gautier, A. & Hinner M. J., eds), pp v-viii, Humana Press, USA (2015).
Gautier, A. & Hinner M. J.

Site-specific protein labeling, Methods and Protocols series (Book)
Methods in Molecular Biology, Vol. 1266, Humana Press, USA (2015).
Gautier, A. & Hinner, M. J. (Editors)

2014

Fluorogen activating and shifting tag (FAST)
Patent Pub. No.: WO/2016/001437, International Application No.: PCT/EP2015/065267.
Gautier, A. & Jullien, L.

How to control proteins with light in living systems.
Nature Chemical Biology 10, 533-541 (2014). 
Gautier, A., Gauron, C., Volovitch, M., Bensimon, D., Jullien, L. & Vriz, S.

Nitric oxide-triggered remodeling of chloroplast bioenergetics and thylakoid proteins upon nitrogen starvation in Chlamydomonas reinhardtii.
Plant Cell 26, 353-372 (2014).
Wei, L., Derrien, B., Gautier, A., Houille-Vernes, L., Boulouis, A., Saint-Marcoux, D., Malnoe, A., Rappaport, F., de Vitry, C., Vallon, O., Choquet, Y. & Wollman, F.-A.

2013

Method for the detection of reversibly photoswitchable fluorescent species (Procédé de détection d’une espèce fluorescente réversiblement photoconvertible).
Patent Pub. No.: WO/2015/075209, International Application No.: PCT/EP2014/075336.
Croquette, V., Gautier, A., Jullien, L., Le Saux, T., Nath, S. S., Querard, J., Wang, P.

Photochemical properties of Spinach and its use in selective imaging.
Chemical Science 4, 2865-2873 (2013). 
Wang, P., Querard, J., Maurin, S., Nath, S. S., Le Saux, T.*, Gautier, A.* & Jullien, L.*

2012

Self-immolation for uncaging with fluorescence reporting.
Angewandte Chemie International Edition 57, 9344-9347 (2012). 
Labruère, R., Alouane, A., Le Saux, T., Aujard, I., Pelupessy, P., Gautier, A., Dubruille, S., Schmidt, F. & Jullien, L.

Modification-free photocontrol of β-lactam conversion with spatio-temporal resolution.
ACS Synthetic Biology 1, 526-531 (2012). 
Venancio-Marques, A., Liu, Y.-J., Diguet, A., di Maio, T., Gautier, A. & Baigl, D.

2011

Genetically encoded photocontrol.
Patent Pub. No.: WO/2011/107747; International Application No.: PCT/GB2011/000304.
Chin, J., Nguyen D. P., Gautier, A., Deiters, A.

Light-activated kinases enable the temporal dissection of signaling networks in living cells.
 Journal of the American Chemical Society 133, 2124-2127 (2011). 
Gautier, A., Deiters, A. & Chin, J.W.

2010

Genetically encoded photocontrol of protein localization in mammalian cells.
Journal of the American Chemical Society 132, 4086-4088 (2010). 
Gautier, A., Nguyen, D.P., Lusic, H., An, W., Deiters, A. & Chin, J.W.

2009

Selective crosslinking of interacting proteins using self-labeling tags.
Journal of the American Chemical Society 131, 17954-17962 (2009). 
Gautier, A., Nakata, E., Lukinavičius, G., Tan, K.T. & Johnsson, K.

The N-C=O interaction: a weak bond with attractive properties for the deliberate exploitation in medicinal and supramolecular chemistry.
In Targets in heterocyclic systems – Chemistry and Properties, Volume 13 (Attanasi, O.A., Spinelli, D., eds.), pp. 1-26, The Royal Society of Chemistry (2009).
Hasserodt, J., Gautier, A., Barbe, R. & Waibel, M.

2008

AGT/SNAP-tag: a versatile tag for covalent protein labeling.
In Probes and tags to study biomolecular function: for proteins, RNA and membranes (Miller, L.W., ed.), pp. 89-107, Wiley-VCH, Weinheim (2008).
Gautier, A., Johnsson, K. & O’Hare, H.M.

An engineered protein tag for multiprotein labeling in living cells.
Chemistry & Biology 15, 128-136 (2008). 
Gautier, A., Juillerat, A., Heinis, C., Correa, I.R., Kindermann, M., Beaufils, F. & Johnsson, K.

2007

Labeling of fusion proteins with synthetic probes.
Patent Pub. No.: WO/2008/012296 ; International Application No.: PCT/EP2007/057597.
Gautier, A., Johnsson, K., Kindermann, M., Juillerat, A. & Beaufils, F.

Chemical probes shed light on protein function.
Current Opinion in Structural Biology 17, 488-494 (2007). 
O’Hare, H.M., Johnsson, K. & Gautier, A.

Observing and manipulating proteins in living cells – Covalent labeling of fusion proteins.
BIOforum Europe 11, 38-40 (2007).
Johnsson, K., O’Hare, H. & Gautier, A.

2006

An unusual functional group interaction and its potential to reproduce steric and electrostatic features of the transition states of peptidolysis.
Bioorganic & Medicinal Chemistry 14, 3835-3847 (2006).
Gautier, A., Pitrat, D. & Hasserodt, J.

2005

Chiral trialkanolamine-based hemicryptophanes: Synthesis and oxovanadium complex.
Organic Letters 7, 1207-1210 (2005). 
Gautier, A., Mulatier, J.-C., Crassous, J. & Dutasta, J.-P.