photo2Our research focuses on the development of chemical tools to observe and manipulate biological processes in new ways, specifically pairing tailor-made synthetic molecules with engineered genetically encodable biomolecules with the goal of obtaining selective and controlled output functions. We aimed in particular at pushing back the frontiers of biological imaging in order to interrogate quantitatively and comprehensively living systems at the molecular, cellular and network levels. This includes the design of innovative probes and methods to advance multiplexing and increase the spatiotemporal resolution of live-cell imaging.

These projects are led within the  Biophysical Chemistry Lab , which gathers scientists interested in manipulating and understanding biological systems in new ways using the knowledge of chemistry.